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1563 مرتبه مشاهده شده
Quantitative genetics
Caballero, Armando,
- ISBN:9781108630542
- ISBN:9781108481410
- ISBN:9781108722353
- Call Number : QH 452 .7 .C3313 2020
- Main Entry: Caballero, Armando, 1960-
- Title:Quantitative genetics [electronic resource] / Armando Caballero.
- Publisher:Madrid, SPain : Author, 2020.
- Physical Description:xv, 326 p.: ill
- Notes:Originally published in Spanish as Genética Cuantitativa (2017) by Editorial Síntesis, Madrid, Spain
- Notes:Includes bibliographical references and index
- Subject:Quantitative genetics.
- Additional formats:Caballero, Armando, 1960- Print version Quantitative genetics Cambridge, United Kingdom ; New York : Cambridge University Press, 2020 9781108481410 (DLC) 2019039768
Quantitative genetics
- Cover
- Half-title page
- Title page
- Copyright page
- Dedication
- Contents
- Preface
- Preface to the Spanish Version
- 1 Continuous Variation
- 2 Forces of Change in the Allele Frequencies
- 2.1 Allele, Gamete and Genotype Frequencies
- 2.2 Hardy–Weinberg Equilibrium
- 2.3 Gametic or Linkage Disequilibrium
- 2.4 Forces of Change in the Allele Frequencies
- 2.5 Genetic Drift: The Ideal Population of Wright–Fisher
- 2.6 Change in Allele Frequencies by Mutation
- 2.7 Change in Allele Frequencies Due to Migration
- 2.8 Change in Allele Frequencies by Natural Selection
- 2.8.1 General Model of Fitness for a Locus
- 2.8.2 Change of Frequency of a Lethal Recessive Allele
- 2.8.3 Change in the Allele Frequency of a Favourable Allele
- 2.8.4 Overdominance and Underdominance
- 2.8.5 Natural Selection and Hardy–Weinberg Disequilibrium
- 2.8.6 Recreation of the Evolutionary Change in the Laboratory
- Problems
- Self-Assessment Questions
- 3 Components of Phenotypic Values and Variances
- 3.1 Decomposition of the Genotypic Value for a Locus
- 3.2 Decomposition of the Genotypic Variance for a Locus
- 3.3 Decomposition of Genotypic Values and Variances for More than One Locus
- 3.4 Concepts of Heritability and Genetic Correlation
- 3.5 The Environmental Deviation and Its Contribution to Phenotypic Variance
- Problems
- Self-Assessment Questions
- 4 Inbreeding and Coancestry
- 5 Effective Population Size
- 5.1 Definition and Methods for the Prediction of the Effective Population Size
- 5.2 Prediction of Ne in Unselected Populations
- 5.3 Prediction of Ne in Selected Populations
- 5.4 Prediction of Ne in Subdivided Populations
- 5.5 Applications of the Theory of Effective Population Size to Conservation
- 5.6 Estimation of Effective Population Size Using Demographic Methods
- 5.7 Estimation of Effective Population Size Using the Allelism of Lethals Method
- 5.8 Estimation of Effective Population Size with Molecular Markers
- 5.9 Estimates of Ne/N in Natural Populations
- Problems
- Self-Assessment Questions
- 6 Estimation of Genetic Values, Variances and Covariances
- 6.1 Estimation of Heritability with Simple Experimental Designs
- 6.1.1 Estimation Based on the Degree of Resemblance between Parents and Offspring
- 6.1.2 Estimation Based on the Degree of Resemblance between Sibs
- 6.1.3 Effect of Assortative Mating
- 6.1.4 Estimation Based on the Degree of Similarity between Twins
- 6.1.5 Coefficients of Additive and Dominance Relationships
- 6.2 Estimation of Genetic Correlation
- 6.3 Estimation of Variance Components and Prediction of Additive Values with Complex Structure of the Data
- 6.3.1 Estimation of Mean and Variance by Maximum Likelihood
- 6.3.2 REML Estimation with the Animal Model
- 6.3.3 Prediction of Additive Values by BLUP
- 6.3.4 Example of BLUP Prediction and BLUE Estimation
- 6.3.5 Use of Molecular Coancestries with Genetic Markers
- 6.3.6 Comparison between Estimates of Heritability with Genealogical and Molecular Data
- Problems
- Self-Assessment Questions
- 6.1 Estimation of Heritability with Simple Experimental Designs
- 7 Mutation
- 7.1 Estimation and Analysis of Mutation in Quantitative Traits
- 7.1.1 Probability of Fixation of a Mutation
- 7.1.2 Estimation of the Rate of Mutation and Mutational Effects
- 7.1.3 Estimation of the Dominance Coefficient
- 7.1.4 Beneficial Mutations and Summary of Mutational Parameters for Fitness
- 7.1.5 Combined Effect of Mutations and Environmental Factors
- 7.1.6 Estimation of Mutational Parameters for Neutral or Quasi-Neutral Traits
- 7.2 Implications of Deleterious Mutations in Populations of Large Size
- 7.3 Mutation and Recombination
- Problems
- Self-Assessment Questions
- 7.1 Estimation and Analysis of Mutation in Quantitative Traits
- 8 Consequences of Inbreeding
- 9 Artificial Selection
- 10 Natural Selection
- 11 Genomic Analysis of Quantitative Traits
- Solutions to Problems and Self-Assessment Questions
- Glossary
- References
- Index